|
This study was designed to investigate the effects of Korean 1% Shanshuyu extract in Pb administered rats. Forty male Sprague-Dawley rats weighed 100 10g were used for this experiment and divided into following 4 group; Con(control group), Shan(1% Shanshuyu extract), Pb(1,000ppm alone lead administered group), Pb-Shan(1,000ppm alone lead administered group with 1% Shanshuyu extract group). Food intake weight and FER(Food efficiency ratio) were remarkably decreased in lead added group. Tissue weight of liver, lung, stomach, heart, kidney and spleen of lead exposed rats were reduced by 1% Shanshuyu extract group. The lead content in the rats tissue of lead alone administered group was lower than in the rats tissue of lead administerd group with 1% Shanshuyu extract group. AST(Asparatate transferase) and ALT(Alanine transferase) were increased in lead-administered group and lower in the 1% Shanshuyu extract group. These results suggested that 1% Shanshuyu extract may have some protective effects fro, of tissue demage induce with Lead.
|